Parasitic dermatitis in dogs: A literature review of clinical and diagnostic aspects and treatment approaches

Mykola Vovk, Svitlana Huralska
Abstract

Parasitic dermatitis in dogs continues to be one of the most common and clinically relevant problems in modern veterinary practice due to its high incidence and considerable influence on animal health status. This study aimed to summarise current data on the prevalence, aetiology, pathogenesis, clinical manifestations, diagnosis, and treatment of dermatitis of parasitic origin in dogs. The study employed methods of analysis and synthesis of scientific literature sources. Parasitic dermatitis was found to have a polyetiological and multifactorial nature and to be most commonly caused by ectoparasites, particularly fleas, lice, chewing lice, and mites. The leading position in the general structure of the disease was taken by flea allergy dermatitis, and acariases, which are of considerable importance due to their high communicability and propensity for a chronic course, play an important role. Clinical signs were non-specific and manifested as pruritus, erythema, alopecia, crusts and scales, and the development of complications related to the development of secondary bacterial and fungal infection, which complicated the differential diagnosis. Laboratory methods for the detection and identification of pathogens using microscopic, serological and molecular genetic methods proved to be one of the main stages in making a diagnosis. Current treatment methods are based on the use of insectoacaricidal drugs, in particular, isoxazolines and macrocyclic lactones, as well as the control of secondary complications and the implementation of preventive measures. The practical value of this study is the systematisation of current scientific approaches to the diagnosis, treatment and prevention of parasitic dermatitis in dogs in order to improve the efficiency of veterinary practice

Keywords

ectoparasites; allergic skin reactions; pathogenesis; diagnosis; insectoacaricidal therapy; secondary infections

Suggested citation
Vovk, M., & Huralska, S. (2026). Parasitic dermatitis in dogs: A literature review of clinical and diagnostic aspects and treatment approaches. Ukrainian Journal of Veterinary Sciences, 17(2), 26-42. https://doi.org/10.31548/veterinary2.2026.26
References
  1. Agu, N.G., Okoye, I.C., Nwosu, C.G., Onyema, I., Iheagwam, C.N., & Anunobi, T.J. (2020). Prevalence of ectoparasites infestation among companion animals in Nsukka cultural zone. Annals of Medical and Health Sciences Research, 10, 1050-1057.
  2. Ali, Y., Barman, A., Abdullah, S.M., Islam, K.B.M.S., & Mohanta U.K. (2020). Morphological identification and prevalence of the dog flea Ctenocephalides Canis (Curtis, 1826) and the cat flea Ctenocephalides Felis (Bouché, 1835) in Dhaka city, Bangladesh. Parasitology, 54(2), 163-172. doi: 10.31857/S1234567806020066.
  3. Amanzougaghene, N., Fenollar, F., Raoult, D., & Mediannikov, O. (2020). Where are we with human lice? A review of the current state of knowledge. Frontiers in Cellular and Infection Microbiology, 9, article number 474. doi: 10.3389/fcimb.2019.00474.
  4. Authoy, A.S., Chanda, A., Datta, A., Al Faruk, S., & Kamal, T. (2023). Prevalence of ectoparasites of dog and cat in Dhaka. Bangladesh. Research Journal of Veterinary Practitioners, 11(4), 42-48. doi: 10.17582/journal.rjvp/2023/11.4.42.48.
  5. Baneth, G., Thamsborg, S.M., Otranto, D., Guillot, J., Blaga, R., Deplazes, P., & Solano-Gallego, L. (2016). Major parasitic zoonoses associated with dogs and cats in Europe. Journal of Comparative Pathology, 155(1), S54-S74. doi: 10.1016/j.jcpa.2015.10.179.
  6. Bates, N., Dijkman, M.A., & Edwards, J.N. (2024). Neurological adverse effects of isoxazoline exposure in cats and dogs. Veterinary Record, 194(12), article number e4149. doi: 10.1002/vetr.4149.
  7. Becskei, C., De Bock, F., Illambas, J., Mahabir, S.P., Farkas, R., & Six, R.H. (2016). Efficacy and safety of a novel oral isoxazoline, sarolaner (Simparica™) in the treatment of naturally occurring flea and tick infestations in dogs presented as veterinary patients in Europe. Veterinary Parasitology, 222, 49-55. doi: 10.1016/j.vetpar.2016.02.007.
  8. Bhusal, R., Gompo, T.R., Sugi, T., Asada, M., & Pandey, K. (2025). Canine demodicosis in Rupandehi Nepal’s street dogs: Prevalence, clinical signs, and hematology. Veterinary Sciences, 12(3), article number 238. doi: 10.3390/vetsci12030238.
  9. Bogdanova, A.Y., Iovenko, A.V., & Koval, G.M. (2024). Monitoring of dermatological pathology of small animals in the conditions of veterinary clinic “Veles” (Mykolaiv). Scientific Messenger of LNU of Veterinary Medicine and Biotechnologies. Series: Veterinary Sciences, 26(114), 38-42. doi: 10.32718/nvlvet11407.
  10. Briceño, C., González-Acuña, D., Jiménez, J.E., Bornscheuer, M.L, Funk, S.M, & Knapp, L.A. (2020). Ear mites, Otodectes cynotis, on wild foxes (Pseudalopex spp.) Chile. Journal of Wildlife Diseases, 56(1), 105-112.
  11. Brue, V., Mosca, M., Briand, A., Bourdeau, P., Pin, D., Cochet-Faivre, N., & Cadiergues, M.C. (2022). Clinical guidelines for the use of antipruritic drugs in the control of the most frequent pruritic skin diseases in dogs. Veterinary Sciences, 9(4), article number 149. doi: 10.3390/vetsci9040149.
  12. Cardoso, A.E.C., Cardoso, A.E.O., Talhari, C., & Santos, M. (2020). Update on parasitic dermatoses. Anais Brasileiros de Dermatologia, 95(1), 1-14. doi: 10.1016/j.abd.2019.12.001.
  13. Chiummo, R., Petersen, I., Plehn, C., Zschiesche, E., Roepke, R., & Thomas, E. (2020). Efficacy of orally and topically administered fluralaner (Bravecto®) for treatment of client-owned dogs with sarcoptic mange under field conditions. Parasit Vectors, 13, article number 524. doi: 10.1186/s13071-020-04395-6.
  14. Chng, L., et al. (2021). Molecular diagnosis of scabies using a novel probe-based polymerase chain reaction assay targeting high-copy number repetitive sequences in the Sarcoptes scabiei genome. PLoS One, 15(2), article number e0009149. doi: 10.1371/journal.pntd.0009149.
  15. Coates, S.J., Thomas, C., Chosidow, O., Engelman, D., & Chang, A.Y. (2020). Ectoparasites. Pediculosis and tungiasis. Journal of the American Academy of Dermatology, 82(3), 551-569. doi: 10.1016/j.jaad.2019.05.110.
  16. Colella, V., et al. (2020). Zoonotic vectorborne pathogens and ecto-parasites of dogs and cats in Eastern and Southeast Asia. Emerging Infectious Diseases, 26(6), 1221-1233. doi: 10.3201/eid2606.191832.
  17. Cornegliani, L., Guidi, E.A., Persico, P., Crisi, P.E., Pignataro, G. Belà, B., & Gramenzi, A. (2024). The beneficial effect of two nutraceuticals in flea allergy dermatitis itch control: A comparative study. International Journal of Nutrition, 8(1), 26-35. doi: 10.14302/issn.2379-7835.ijn-24-5098.
  18. Dantas-Torres, F., et al. (2020). TroCCAP recommendations for the diagnosis, prevention and treatment of parasitic infections in dogs and cats in the tropics. Veterinary Parasitology, 283, article number 109167. doi: 10.1016/j.vetpar.2020.109167.
  19. Defalque, V.E. (2022). Isoxazolines for treating canine demodicosis, sarcoptic mange (scabies), and lice infestation. Canadian Veterinary Journal, 63(11), 1159-1162.
  20. Derevianchenko, O., & Petrov, R. (2023). Monitoring of the episototic situation regarding causes of ectoparasites of dogs and cats in Sumy. Bulletin of Sumy National Agrarian University: Veterinary Medicine, 4(63), 9-14. doi: 10.32782/bsnau.vet.2023.4.2.
  21. Dumitrache, M.O., & Cadiergues, M. (2023) The most effective systemic treatment in dogs with sarcoptic mange: A critically appraised topic. BMC Veterinary Research, 19, article number 189. doi: 10.1186/s12917-023-03759-1.
  22. El Hamzaoui, B., Zurita, A., Cutillas, C., & Parola, P. (2020). Fleas and flea-borne diseases of North Africa. Acta Tropica, 211, article number 105627. doi: 10.1016/j.actatropica.2020.105627.
  23. Fouda, M.A., Abdel-Saeed, H., Abdelgayed, S.S., & Abdou, O.M. (2021). Clinical, haematobiochemical, and histopathological studies on some dermopathies in dogs. Advances in Animal and Veterinary Sciences, 9(1), 94-102. doi: 10.17582/journal.aavs/2021/9.1.94.102.
  24. Gaens, D., Rummel, C., Schmidt, M., Hamann, M., & Geyer, J. (2019). Suspected neurological toxicity after oral application of fluralaner (Bravecto®) in a Kooikerhondje dog. BMC Veterinary Research, 15(1), article number 283. doi: 10.1186/s12917-019-2016-4.
  25. Gholinezhad, D., Bahrampour, R., Bazneshin, A.N., & Nokhostin, A.H. (2023). Diagnosis and treatment of Demodicosis in pet dogs with dermatological lesions by Amitraz in Tabris, Iran. International Journal of Medical Parasitology, Epidemiology and Sciences, 4(3), 76-79. doi: 10.34172/ijmpes.3141.
  26. Gonçalves, I.L., das Machado Neves, G., Porto Kagami, L., Eifler Lima, V.L., & Merlo, A.A. (2021). Discovery, development, chemical diversity and design of isoxazoline based insecticides. Bioorganic & Medicinal Chemistry, 30, article number 115934. doi: 10.1016/j.bmc.2020.115934.
  27. Guillot, J., & Bond, R. (2020). Malassezia yeasts in veterinary dermatology: An updated overview. Frontiers in Cellular and Infection Microbiology, 10, article number 79. doi: 10.3389/fcimb.2020.00079.
  28. Gupta, A.K, Wang, T., Talukder, M., & Bakotic, W.L. (2025). Global dermatophyte infections linked to human and animal health: A scoping review. Microorganisms, 13(3), article number 575. doi: 10.3390/microorganisms13030575.
  29. Hobi, S., Bęczkowski, P.M., Mueller, R., Tse, M., & Barrs, V.R. (2024). Malassezia dermatitis in dogs and cats. The Veterinary Journal, 304, article number 106084. doi: 10.1016/j.tvjl.2024.106084.
  30. Ilie, M.S., Imre, M., Giubega, S., Luca, I., Florea, T., & Morariu, S. (2021). Feline demodicosis case report-First molecular characterization of Demodex mites in Romania. Pathogens, 10(11), article number 1474. doi: 10.3390/pathogens10111474.
  31. Kazemi, M. (2025). Revolutionizing veterinary medicine: The role of nanoparticles in advancing animal health, nutrition and disease management. Veterinary Medicine and Science, 5, article number e70528. doi: 10.1002/vms3.70528.
  32. Kruchynenko, O.V. (2020). Ectoparasites of dogs and cats (spreading and treatment). Bulletin of Poltava State Agrarian Academy, 3, 241-250. doi: 10.31210/visnyk2020.03.28.
  33. Kumar, P., & Shekhar, S. (2020). Occurrence of dermatological disorders and haemato-biochemical alteration, treatment of demodicosis in dogs. Journal of Entomology and Zoology Studies, 8(2), 125-132.
  34. Lara-Reyes, E., Quijano-Hernández, I.A., Rodríguez-Vivas, R.I., Del Ángel-Caraza, J., & Martínez-Castañeda, J.S. (2021). Factors associated with endoparasites and ectoparasites in domiciled dogs in the metropolitan area of Toluca, México. Biomedica: Revista del Instituto Nacional de Salud, 41(4), 756-772. doi: 10.7705/biomedica.6013.
  35. Loeffler, A., Cain, C.L., Ferrer, L., Nishifuji, K., Varjonen, K., Papich, M.G., Guardabassi, L., Frosini, S.M., Barker, E.N., & Weese, J.S. (2025). Antimicrobial use guidelines for canine pyoderma by the International Society for Companion Animal Infectious Diseases (ISCAID). Veterinary Dermatology, 36(3), 234-282. doi: 10.1111/vde.13342.
  36. Martínez-Ibañez, F., Cruz-Vázquez, C., Vitela-Mendoza, I., Lagnes-Quintanille, R., & Medina-Esparza, L. (2026). Detection of coumaphos, fipronil, flumethrin and amitraz susceptibility in Rhipicephalus sanguineus s.l. (Acari: Ixodidae) from Mexico. Veterinary Research Communications, 50, article number 54. doi: 10.1007/s11259-025-10986-4.
  37. Mason, K., & Ruutu, M. (2023). Canine dermatitis on contacting grass leaf: A case series. Veterinary Dermatology, 34(2), 115-124. doi: 10.1111/vde.13143.
  38. Melezhyk, А., Korchan, L., Dmitrenko, N., & Zamaziy, A. (2024). Features of the course of otodectosis in mixtinvasions of dogs and cats. Scientific Progress and Innovations, 27(2), 128-132. doi: 10.31210/spi2024.27.02.22.
  39. Michalka, A.D., Deak, G., Panait, L., Rabei, S., & Beugnet, F. (2022). Efficacy of afoxolaner (NexGard®) against natural infestations with Trichodectes canis in dogs under field conditions. Parasites & Vectors, 15, article number 317. doi: 10.1186/s13071-022-05428-y.
  40. Miller, J., Simpson, A., Bloom, P., Diesel, A., Friedeck, A., Paterson, T., Wisecup, M., & Yu, C.M. (2023). 2023 AAHA management of allergic skin diseases in dogs and cats guidelines. Journal of the American Animal Hospital Association, 59(6), 255-284. doi: 10.5326/JAAHA-MS-7396.
  41. Moog, F., Brun, J., Bourdeau, P., & Cadiergues, M.C. (2021). Clinical, parasitological, and serological follow-up of dogs with sarcoptic mange treated orally with lotilaner. Case Reports in Veterinary Medicine, 25, article number 6639017. doi: 10.1155/2021/6639017.
  42. Mueller, R.S., Bensignor, E., Ferrer, L., Holm, B., Lemarie, S., Paradis, M., & Shipstone, M.A. (2012). Treatment of demodicosis in dogs: 2011 clinical practice guidelines. Veterinary Dermatology, 23(2), 86-96. doi: 10.1111/j.1365-3164.2011.01026.x.
  43. Nguyen, Y.T.H., Tran, G.T.H., & Vu, T.T.T. (2025). Molecular identification of the fleas Ctenocephalides Felis and tapeworm Dipilydium caninum isolated from fleas in companion dogs and cats around Hanoi, Vietnam. International Journal of Veterinary Science,14(3), 487-491. doi: 10.47278/journal.ijvs/2024.278.
  44. Nogueira, B.C.F., da Silva Soares, E., Mauricio Ortega Orozco, A., Abreu da Fonseca, L., & Kanadani Campos, A. (2023). Evidence that ectoparasites influence the hematological parameters of the host: A systemat-ic review. Animal Health Research Reviews, 24(1), 28-39. doi: 10.1017/S1466252323000051.
  45. Panait, L.C., Safarov, A., Deak, G., Ionicǎ, A.M., & Michalka, A.D. (2025). Diversity of lice and flea- and lice-borne pathogens in free-ranging dogs in Uzbekistan. Medical and Veterinary Entomology, 39(1), 216-222. doi: 10.1111/mve.12769.
  46. Prohic, A. (2024). Parasitic and protozoan skin infections. In Dermatovenerology (pp. 141-151). Cham: Springer. doi: 10.1007/978-3-031-66131-0_8.
  47. Romero-Núñez, C., Guiliana Bautista-Gómez, L., Sheinberg, G., Martín-Cordero, A., Flores-Ortega, A., & Heredia-Cárdenas, R. (2020). Efficacy of afoxolaner plus milbemycin oxime in the treatment of canine demodicosis. International Journal of Applied Research in Veterinary Medicine, 17, 35-41.
  48. Tadesse, T., Tilahun, B., Hailu, S.M., & Alemu, S. (2019). Prevalence and species distribution of ectoparasite of domesticdogs in jimma town, Oromia regional state, southwest Ethiopia. Journal of Entomology and Zoology Studies, 7(2), 1154-1157.
  49. Thomson, P., Carreño, N., & Núñez, A. (2023). Main mites associated with dermatopathies present in dogs and other members of the Canidae family. Open Veterinary Journal, 13(2), 131-142. doi: 10.5455/OVJ.2023.v13.i2.1.
  50. Varloud, M., & Fourie, J.J. (2015). One-month comparative efficacy of three topical ectoparasiticides against adult brown dog ticks (Rhipicephalus sanguineus sensu lato) on mixed-bred dogs in controlled environment. Parasitology Research, 114(5), 1711-1719. doi: 10.1007/s00436-015-4356-8.
  51. Yevstafieva, V., & Horb, K. (2020). Age dynamics of infestation of dogs Ctenocephalides spp. Scientific Messenger of LNU of Veterinary Medicine and Biotechnologies, 22(98), 84-87. doi: 10.32718/nvlvet9815.
  52. Yevstafieva, V., Plakhotna, Y., Melnychuk, V., Yuskiv, I., Korchan, L., Kanivets, N., & Slynko, V. (2024). Characteristics of the course of acaroses in dogs caused by parasitism of acariform ticks. Scientific Progress and Innovations, 27(4), 115-119. doi: 10.31210/spi2024.27.04.19.
  53. Yuskiv, I.D., Tishyn, O.L., & Yuskiv, L.L. (2024). Evaluation of efficacy of a drug based on fipronil, ivermectin, and pyriproxyfen against ecto- and endoparasitic invasions of dogs and cats. Regulatory Mechanisms in Biosystems, 15(1), 113-118. doi: 10.15421/022417.
  54. Yuskiv, I.D., Tishyn, O.L., & Yuskiv, L.L. (2025). A medical drug based on fipronil, dinotefuran, and pyriproxyfen for treatment of ectoparasitic infestations of dogs and cats. Regulatory Mechanisms in Biosystems, 16(2), article number e25089. doi: 10.15421/0225089.
  55. Zineldar, H.A., Abouzeid, N.Z., Eisa, M.I., Bennour, E.M., & Neshwy, W.M.E. (2023). Prevalence, clinical presentation, and therapeutic outcome of ectoparasitic infestations in dogs in Egypt. Open Veterinary Journal, 13(12), 1631-1644. doi: 10.5455/ovj.2023.v13.i12.13.