Cardiogenic and non-cardiogenic pulmonary oedema in a domestic cat: Pathological mechanisms, differential diagnosis, and treatment

Tetiana Zamorska, Nataliia Grushanska
Abstract

The relevance of this study is conditioned upon the prevalence of pulmonary oedema in cats and special approaches to their therapy. In this regard, this paper is aimed at identifying aetiological factors, breed predisposition, clinical manifestations, haematological parameters, and radiological signs. Leading in the study of this issue is an integrated approach, which includes consideration of the aetiology, pathogenesis, diagnosis of cardiogenic and non-cardiogenic pulmonary oedema and treatment of cats. It was found that in the conditions of the “Vet House” Veterinary Centre (Vinnytsia), cats of the British Shorthair, Sphinx, Maine Coon breeds and their hybrids were most often registered with this pathology. 68 cats were diagnosed with cardiogenic pulmonary oedema due to hypertrophic, restrictive, and unclassified cardiomyopathy. 42 animals were found to have non-cardiogenic pulmonary oedema due to traumatic brain injury, toxic substance poisoning, anaphylactic reaction, airway obstruction, and electric shock. It was found that the most informative during the differential diagnosis of pulmonary oedema in cats are the results of echocardiography and X-ray examination. It was established that for the differential diagnosis of cardiogenic and non-cardiogenic pulmonary oedema, clinical indicators and results of haematological examination of animals are low in information. It was discovered that therapeutic measures for pulmonary oedema are effective in considering aetiological factors, although at the first stage, for both forms of pulmonary oedema, they are aimed at reducing and eliminating the manifestations of acute respiratory failure. The materials of this paper are of practical value for veterinary doctors of general practice and intensive care on differential diagnosis, prediction of the development of the disease and effective treatment of cats

Keywords

biochemical and morphological parameters of blood, shortness of breath, interstitial pattern, pathogenesis, radiography

Suggested citation
Zamorska, T., & Grushanska, N. (2022). Cardiogenic and non-cardiogenic pulmonary oedema in a domestic cat: Pathological mechanisms, differential diagnosis, and treatment. Ukrainian Journal of Veterinary Sciences, 13(1), 34-43. https://doi.org/10.31548/ujvs.13(1).2022.34-43
References

[1] Fuentes, V.L., Abbott, J., Chetboul, V., Côté, E., Fox, Ph.R., Häggström, J., Kittleson, M.D., Schober, K., Stern, J.A. (2020). ACVIM consensus statement guidelines for the classification, diagnosis, and management of cardiomyopathies in cats. Journal of Veterinary Internal Medicine, 34(3), 1062-1077. doi: 10.1111/jvim.15745.

[2] Kittleson, M.D. & Côté, E. (2021). The feline cardiomyopathies: 1. general concepts. Journal of Feline Medicine and Surgery, 23(11), 1009-1027. doi: 10.1177/1098612X211021819.

[3] Łobaczewski,  A., Czopowicz,  M., Moroz,  A., Mickiewicz,  M., Stabińska,  M., Petelicka,  H., Frymus,  T., & SzaluśJordanow, O. (2021). Ultrasound for imaging of B-lines in dogs and cats – a prospective study investigating agreement between three types of transducers and the accuracy in diagnosing cardiogenic pulmonary edema, pneumonia and lung neoplasia. Animals, 11(11), 3279. doi: 10.3390/ani11113279.

[4] Rauserova-Lexmaulova, L., Agudelo, C., & Prokesova, B. (2021). Acute respiratory failure after administration of hydrogen peroxide as an emetic in a cat. Case Reports in Veterinary Medicine, 7242631, 1-6. doi: 10.1155/2019/7242631.

[5] Bachmann, M., & Waldrop, J.E. (2018). Noncardiogenic pulmonary edema. Bulger Veterinary Hospital. Retrieved from https://studylib.net/doc/8713890/noncardiogenic-pulmonary-edema.

[6] Root,  M., & Cavanagh,  K. (2018). Heart disease in cats. Сanadian Veterinary Medical Association. Retrieved from https://www.canadianveterinarians.net/documents/heart-disease-in-cats.

[7] Kostiuk, O.S., Yakimchiuk, O.N., & Maryniuk, N.O. (2020). Risk assessment of death in cats with cardiomyopathy in case of cardiogenic pulmonary edema. Ukrainian Journal of Veterinary Sciences, 11(1), 34-42. doi: 10.31548/ujvs2020.01.004.

[8] Macintire, D.K., Drobatz, K.J., Haskins, S.C., & Saxon, W.D. (2005). Manual of small animal emergency and critical care medicine. New Jersey: Wiley-Blackwell.

[9] Ward, J., Lisciandro, G., Keene, B., Tou, S., & DeFrancesco, T. (2018). Accuracy of point-of-care lung ultrasonography for the diagnosis of cardiogenic pulmonary edema in dogs and cats with acute dyspnea. Journal of the American Veterinary Medical Association, 250(6), 666-675. doi: 10.2460/javma.250.6.666.

[10] Drobatz, J.K., Hopper, K., Rozanski, E.A., & Silverstein, D.C. (2019). Textbook of small animal emergency medicine. New Jersey: Wiley-Blackwell.

[11] Ruby, J., Secrest, S., & Sharma, A. (2020). Radiographic differentiation of mediastinal versus pulmonary masses in dogs and cats can be challenging. Veterinary Radiology & Ultrasound, 61(4), 385-393. doi: 10.1111/vru.12859.

[12] Adamantos, S. (2021). Fluid therapy in pulmonary disease: How careful do we need to be? Frontiers in Veterinary Science, 8, 624-833. doi: 10.3389/fvets.2021.624833.

[13] Johnson, L.R. (2020). Canine and feline respiratory medicine. New Jersey: Wiley-Blackwell. doi: 10.1002/9781119482307.

[14] Diamond,  M., Peniston,  H.L., Sanghavi,  D., & Mahapatra,  S. (2021). Acute respiratory distress syndrome. Treasure Island (FL): StatPearls Publishing.

[15] European Convention for the protection of vertebrate animals used for research and other scientific purposes. (1986, March). Retrieved from http://zakon2.rada.gov.ua/laws/show/994_137.

[16] European Convention for the protection of pets. (2013, September). Retrieved from https://zakon.rada.gov.ua/laws/ show/994_a15#Text.

[17] Law of Ukraine No. 3447-IV “On the Protection of Animals from Cruel Treatment”. (2006, February). Retrieved from https://zakon.rada.gov.ua/laws/show/3447-15#Text.

[18] Diana, A., Perfetti, S., Rigo, F., Baron Toaldo, M., Pey, P., Cipone, M., Poser, H., & Guglielminі, C. (2019). Radiographic features of cardiogenic pulmonary edema in the cat: 71 cases. Retrieved from https://www.evdi-congress.eu/resources/ media/Poster_abstracts/Simone_Perfetti_RADIOGRAPHIC_FEATURES_OF_CARDIOGENIC_PULMONARY_EDEMA_ IN_THE_CAT_71_CASES_.pdf

[19] Ettinger, S.J., Feldman, E.C., & Cote, E. (2018). Textbook of veterinary internal medicine. Philadelphia: Saunders.

[20] McGavin, M.D., Carlton, W.W., & Zachary, J.F. (2001). Thompson's special veterinary pathology. Saint Louis: Mosby.

[21] Clark, Sh.B., & Soos, M.P. (2022). Noncardiogenic pulmonary edema. In StatPearls. Treasure Island (FL): StatPearls Publishing. Retrieved from https://pubmed.ncbi.nlm.nih.gov/31194387.

[22] Sharp,  C.R. (2015). Approach to respiratory distress in dogs and catsToday’s Veterinary Practice. Retrieved from https://todaysveterinarypractice.com/approach-to-respiratory-distress-in-dogs-and-cats.