Ukrainian Journal of Veterinary Sciences

Presented results of histological investigation of liver and kidneys of 8 cats died (n = 6) or euthanized (n = 2) at the suspicion to the infectious peritonitis on the base of results of ultrasound investigation, polymerase chain reaction, clinical sings and hematology. Diagnosis was confirmed at the dissection. At the necropsy there was find sings of icterus in skin, subcutaneous fat, sclera, pleura, and things of the sero-purulent rhinitis and conjunctivitis. All subcutaneous lymph nodules was enlarge, with yellowish color. In abdominal cavity there was up to 500 milliliters of transparent, viscous, light yellow fluid. The liver was covered by the fibrin deposits. Under such deposits, there was many grayish-white knots. Similar knots found on the kidney surface. Microscopically in the liver found things of hepatitis, cholestasis, and degenerative changes and necrosis of hepatocytes. In kidneys found proliferative glomerulonephritis, which in some cases accompanied with the partial necrosis of glomeruli and destroying of some renal corpuscles. In the renal tubular epithelium find sings of cellular swelling, hydropic degeneration and focuses of coagulative necrosis. In kidney stroma, find the sites of lymphocytes, monocytes and some macrophages infiltration. In part of blood vessels registered thrombi. All this microscopic changes permit to conclude, that the feline infectious peritonitis lead to the development of the hepatorenal syndrome. 

cats, feline infectious peritonitis, liver, kidneys, gross changes, microscopic changes, hepatorenal syndrome