Ukrainian Journal of Veterinary Sciences

Ophthalmologic pathology of cattle is one of the most common and complex unsolved problems of modern veterinary surgery. Uveitis is a very dangerous and severe lesion of the choroid of the eye (tractus uveus), as it is often complicated by cataracts or glaucoma, which inevitably result in blindness. The article highlights the results of a study of the killer activity of cattle lymphocytes, a patient with streptococcal uveitis. According to modern ideas, in the pathogenesis of uveitis, a significant role is played by immune disorders, including those caused by K-cells (killers). At the same time, the state of the effector link of the immune system, in particular, the killer activity of lymphocytes during uveitis remains poorly known, which was the goal of our study. During this study, a clinical, hematological, microbiological and pathoanatomical examination of 75 young cattle at the age of 9-15 months, a patient with fibrinous uveitis, was carried out. It was determined that an increase in the content of K-cells in the blood during the first two stages of affection of the patient with fibrinous uveitis of streptococcal etiology in young cattle can be considered as an antimicrobial protection, while an increase in the content of killers in the third stage of the disease is due to effector activity, with resorbtion of the lens.

streptococcal uveitis, eye, cattle, killer activity, lymphocytes, K cells, tractus uveus, hemato-ophthalmic barrier