Ukrainian Journal of Veterinary Sciences

The article presents the results of a toxic biological evaluation of meat (in the muscles of the thigh, pectoral muscles, and the muscles of the lower leg) of broiler chickens using an express method using the infusoria Tetrahimena pyriformis using the Baitril 10 % preparation. For the bird of experimental group, this preparation was used by oral administration at the rate of 0.1 ml/kg of body weight for 5 days. The broiler chickens of control and experimental groups were slaughtered on day 6, day 12 and day 14 after the last administration of the drug. For the toxicological evaluation, the muscles with the highest residual enrofloxacin content were used.The criterion for toxicity in biotesting on infusoria is a probable decrease in the number of cells in the culture in 24 hours. It has was been established that when using the veterinary drug the meat of broiler chickens, was not toxic to infusoria Tetrachimena pyriformis already on days 6 after the last feeding . The indicator of the relative biological value of pectoral muscles, muscles of the thigh and lower leg is close by value and tends to increase the relative biological value of the muscles of the research group already on the 14th day after the last application of the veterinary drug. 

toxicity, biological evaluation, enrofloxacin, fluoroquinolones, Tetrachimena pyriformis